Arsenic-Specific Stem Cell Selection During Malignant Transformation
نویسندگان
چکیده
منابع مشابه
Arsenic-specific stem cell selection during malignant transformation.
BACKGROUND Arsenic is a carcinogen that targets the urogenital system, including the prostate. Although the mechanisms for arsenic-induced carcinogenesis are undefined, arsenic drives overaccumulation of stem cells and cancer stem cells (CSCs) in vivo and in vitro, indicating that these cells are a key target population. Disruption of stem cell population dynamics may be critical to acquisition...
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ژورنال
عنوان ژورنال: JNCI: Journal of the National Cancer Institute
سال: 2010
ISSN: 1460-2105,0027-8874
DOI: 10.1093/jnci/djq093